Game crashes

[JPCosta92]

Since the last update, my game crashes a lot, preventing me from building a given prison for more than a few dozen minutes at a time. I cannot continue that prison, but I can sell it (using a savegame prior to the crash) and start a new one. And then the game crashes again, repeating the process. Each prison always crashes at a specific point (like building a certain utility, or assigning a cell).
It renders PA absolutely unplayable.
Also, to make matters worse, PA only launches once. Meaning, if I exit the game (or it crashes, which it will), and I try to restart it, my PC locks. Completely. The only solution (!) is a hard reset.
Does anyone have similar problems?
I have used mods, but have removed them, uninstalled the game, deleted related files and folders, etc., reinstalled the game and the problem persists on two PCs, one running Windows 8.1 and one running Windows 7.
I hadn't played PA for a few months and I was still running update 3 until now, without a single serious issue.
Any help?
Thanks in advance!

Edit: Forgot to say I have the GOG version, not the Steam one.