Here is [the thread about gameplay issues
The beta patch helped with the constant crashes. Overall gameplay is much better.
But, if I try Xander's fix (to be able to place armor), that is to put ControlMouse=2 in the preferences.txt file, the program will reliably crash as soon as I try to use a right mouse button to fire a 2nd weapon.
It also crashed before the beta patch, and now after it, crashes about half the time when I zoom in on an incubator where there's lots going on, souls coming in, engineers floating around, DGs doing their thing, and try to do something with an officer.
I'm currently stuck on pattern buffer level, but I figured out how to place armor at least, using preferences that say I have a 1 button mouse (mine has 2), placing armor with either button, then squeezing both buttons to deploy the armor. This seems to work, and doesn't crash it.
Edit: Just tried it again, it still crashes in pattern buffer when I'm zoomed in on an incubator, lots going on, and try to place a program with a mouse
This time, it was a squad. So I don't know if it's a mouse issue or what.
But the reason I posted in this thread was to find out if you think starting a new, post-beta profile will help with the crashes. I'm still using the profile I began pre-beta.