Forgive my stupidity, but what is ISS?

Also there is, at least on mine, a confirmation stating data has been changed.

Steam has given me version 1.54 of uplink. I can't get some things to work out right. such as the hud proxy bypass. There doesn't appear to be anyway to get it to fire up, yes I started the program, just can't get it to go. Also after getting the HUD, my proxy disable seems to work but when updating...